CALL FOR PAPERS Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies Resolvin E1 normalizes contractility, Ca sensitivity and smooth muscle cell migration rate in TNF- - and IL-6-pretreated human pulmonary arteries
نویسندگان
چکیده
Roddy Hiram, Edmond Rizcallah, Sofia Marouan, Chantal Sirois, Marco Sirois, Caroline Morin, Samuel Fortin, and Eric Rousseau Department of Pharmacology and Physiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Obstetrics-Gynecology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Pathology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Service of Thoracic Surgery, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada; and SCF Pharma, Ste-Luce, Quebec, Canada
منابع مشابه
Resolvin D1 reverses reactivity and Ca2+ sensitivity induced by ET-1, TNF-α, and IL-6 in the human pulmonary artery.
Pulmonary hypertension (PH) is a rare and progressive disease characterized by an inflammatory status and vessel wall remodeling, resulting in increased pulmonary artery resistance. During the last decade, treatments have been proposed; most of them target the endothelial pathways that stimulate smooth muscle cell relaxation. However, PH remains associated with significant morbidity. We hypothe...
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تاریخ انتشار 2015